When running to First Base, be sure to run to the right-side bag. There are two bags at first base. To minimize collisions, the first baseman has the left-side bag for making plays and the runner goes to the right-side bag. If you run to the left-side bag, you'll be called out.
One exception to this rule is if you get a hit thru the infield which doesn’t involve a play at first base then you don’t have to touch the outside base when rounding first base.
When running to Home Plate, be sure to run to the right-side plate. At home plate, there are two plates. The plate where you bat is where the catcher makes plays. The runner goes to a second plate that is 8 feet way. If you run to the wrong plate, you are out.
Also be aware that there is a "commit" line along the third base line located 30 feet from home plate. Once you cross that line, you cannot return to third base.
Play at the Plate is a Force Out. The plays at Home Plate are called like they are at First Base, if the catcher has the ball and is touching Home Plate before you cross the running plate, you are called out. Accordingly, there is no need or benefit to slide.
For Obvious Double Plays, Runner to 2nd Must Run to Clear of Throwing Lane to 1st. To reduce risk of injury, when it is obvious a runner to 2nd will be out on a double play attempt, that runner must clear the throwing lane to 1st, either by tailing off toward the outfield or by sliding short of the base. Any contact or interference with the defensive player making the play at 2nd base is an automatic double play. If fielders do not make the play (e.g., dropped ball, bad throw), the runner wis awarded 2nd base).